Plasticity of Brain-Behavior Change


Object-Location Memory (OLM) project: Brain structural and functional correlates

The OLM project is a previously completed cognitive training study in which healthy elderly adults underwent either process-based training of the ability to learn and remember object-location associations or an active control condition. Primary behavioral results, which have already been published, indicate that training led to improvements in the object-location memory tasks as well as in the domains of spatial episodic memory (near-transfer) and reasoning (far-transfer). Current analyses incorporate structural and functional neuroimaging data in order to elucidate individual predictors of training-related cognitive improvements, identify brain regions affected by OLM training, and examine temporal trajectories of brain activity across the training period. 

Project status: ongoing
Contact: Dr. Ania Mikos



Hotel Plastisse study: Expertise-related functional brain network efficiency in healthy older adults

In this study, three groups of healthy older participants aged 61 to 75 years with different training histories (multi-domain, single-domain visuomotor, no training) were compared with regard to their functional brain network characteristics. Therefore, a high-density EEG-measurement was conducted one year after training to calculate the efficiency of functional brain networks. In terms of the functional brain network features, the multi-domain group showed significantly higher functional connectivity in a network encompassing visual, motor, executive, and memory-associated brain areas in the theta frequency band as well as an enhanced processing efficiency compared to the single-domain visuomotor group. Behaviorally, the multi-domain group performed significantly better than the visuomotor and the control group on a multi-domain task.

Project status: completed in 2018
Contact: Dr. Christina Röcke